abstract：:In this study, we investigated the protective effect of pentoxifilline (PTX) on smoking-induced damage in rat kidney tissues. Twenty-seven male Wistar rats were used in the study. Animals were divided into three equal groups as follows: Group 1: control group with only normal saline (NS; 0.9% NaCl) injection for 8 wee...

journal_title：Toxicology and industrial health

authors： Ozkurkcugil C,Yilmaz MY,Ozkan L,Kokturk S,Isken T

更新日期：2011-05-01 00:00:00

abstract：:The aim of this study was to evaluate indoor air quality and factors affecting expired carbon monoxide (CO) levels in a coffeehouse environment. This cross-sectional study was conducted at 16 randomly selected coffeehouses in Duzce, Turkey, during November 2007 to March 2008. A total of 547 people, average age 46.72 ±...

journal_title：Toxicology and industrial health

authors： Bahcebasi T,Kandis H,Baltaci D,Kara IH

更新日期：2011-04-01 00:00:00

abstract：:Aluminum (Al) is commonly used in industrial processes and drugs and is thought to induce erythrocytes damage via activation of oxidative stress. Recently, bismuth (Bi)-containing drugs are used in the treatment of various diseases. However, uncertain effects of Bi in blood tissue may participate in the therapeutic ef...

journal_title：Toxicology and industrial health

authors： Turkez H,Geyikoglu F

更新日期：2011-03-01 00:00:00

abstract：:Acrylamide has been discovered in foods cooked at high temperature. A potentially harmful effect of this dietary component has been suggested by data indicating its association with increased breast cancer. This study investigated the potential effects of acrylamide in nontumorigenic breast cells by assessing expressi...

journal_title：Toxicology and industrial health

authors： Lyn-Cook LE Jr,Tareke E,Word B,Starlard-Davenport A,Lyn-Cook BD,Hammons GJ

更新日期：2011-02-01 00:00:00

abstract：:Atmospheric acid precursor emissions in Asia are increasing at a significant rate. This is expected to continue for the next several years. This main purpose for this study is to observe the concentration variations of PM(2.5), PM(2.5-10), PM(10), total suspended particulates (TSP), atmospheric particulates, and dry d...

journal_title：Toxicology and industrial health

authors： Fang GC,Liu CK

更新日期：2010-10-01 00:00:00

abstract：:Some studies have shown increased DNA damage among car painters, but other professionals working in auto body and paint shops have not been extensively assessed. The aim of this study was to assess DNA damage in different types of auto body shop workers by measuring micronucleus (MN) levels in exfoliated buccal cells....

journal_title：Toxicology and industrial health

authors： Siebel AM,Basso da Silva L

更新日期：2010-10-01 00:00:00

abstract：:The morphological consequences of chronic exposition to low doses of cadmium (Cd) in the Leydig cells population were investigated in 40 sexually mature male mice at morphological and ultrastructural levels. Animals were orally exposed to cadmium (0.015 g/L of CdCl(2) in drinking water) for 3, 6, 12 and 18 months and ...

journal_title：Toxicology and industrial health

authors： Blanco A,Moyano R,Molina López AM,Blanco C,Flores-Acuña R,García-Flores JR,Espada M,Monterde JG

更新日期：2010-09-01 00:00:00

abstract：:The aim of this study was to investigate the different testicular toxicity and the role of apoptosis in the possible mechanism induced by the two isomers of bromopropanes (BPs) in the same dosage. Following the 14-day treatment with a single dose of 1-BP and 2-BP (1 g/kg), male rats were killed and a series of experim...

journal_title：Toxicology and industrial health

authors： Xin QQ,Yong Huang,Jie Li,Zhang WJ,Tao Yu,Hua Wang,Cheng Zhang,Ye DQ,Fen Huang

更新日期：2010-09-01 00:00:00

abstract：:People live in the mountains distributed across the world and are exposed to reduced inspired oxygen and lower barometric pressure along with other factors that lead to high-altitude diseases. The present study was conducted to examine what extent of marketed medicines used in the management of high-altitude sickness ...

journal_title：Toxicology and industrial health

authors： Ghosh M,Biswas D,Mukherjee A

更新日期：2010-08-01 00:00:00

abstract：:Arsenic is an ubiquitous and well-documented carcinogenic metalloid. The most common source of arsenic is drinking water. The mechanism of arsenic toxicity in a cell has historically been centered around its inhibitory effects on cellular respiration and mitochondrial injury. Ascorbic acid, a low molecular weight, wat...

journal_title：Toxicology and industrial health

authors： Singh S,Rana SV

更新日期：2010-06-01 00:00:00

abstract：:Insulin resistance (IR) is recognized as a contributory factor for a variety of liver diseases. The present study investigates the susceptibility of liver to the toxic actions of carbon tetrachloride (CCl(4)) in a rat model of IR, induced by feeding a high-fructose diet (60 g/100 g) for 30 days. A sub-lethal dose of C...

journal_title：Toxicology and industrial health

authors： Pooranaperundevi M,Sumiyabanu MS,Viswanathan P,Sundarapandiyan R,Anuradha CV

更新日期：2010-03-01 00:00:00

abstract：:This study demonstrates the detection and dynamics of macrocyclic trichothecene mycotoxin (MTM) tissue loading using a commercially available assay in a goat model. The detection of MTMs has been difficult and complex due to the uncertainty of what tissues to examine and when to sample. Twelve goats (two groups of eac...

journal_title：Toxicology and industrial health

authors： Layton RC,Purdy CW,Jumper CA,Straus DC

更新日期：2009-10-01 00:00:00

abstract：:The following is a review of some of the work we have done since 2004 regarding the importance of molds and their mycotoxins in the phenomenon of sick building syndrome (SBS). In these studies we showed that the macrocyclic trichothecene mycotoxins (MTM) of Stachybotrys chartarum (SC) are easily dissociated from the s...

journal_title：Toxicology and industrial health

authors： Straus DC

更新日期：2009-10-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of resveratrol on kidney tissue of rats exposed to cigarette smoke. Forty adult male Wistar Albino rats were divided into four groups. Animals in group 1 was the control group. For 6 weeks, group 2 was exposed to cigarette smoke; group 3 received daily intraperitoneal i...

journal_title：Toxicology and industrial health

authors： Kuruş M,Ugras M,Esrefoglu M

更新日期：2009-09-01 00:00:00

abstract：:Widespread use of mobile phones which are a major source of electromagnetic fields might affect living organisms. However, there has been no investigation concerning prenatal exposure to electromagnetic fields or their roles in the development of the pyramidal cells of the cornu ammonis in postnatal life. Two groups o...

journal_title：Toxicology and industrial health

authors： Bas O,Odaci E,Mollaoglu H,Ucok K,Kaplan S

更新日期：2009-07-01 00:00:00

abstract：:The antioxidant power of the so-called antioxidants is negligible because their rate constants and concentrations are too small to compete with the specialized defense enzymes, like superoxide dismutase (SOD), for the reactive oxygen species. In this short review, we present a number of experimental data of our group,...

journal_title：Toxicology and industrial health

authors： Koltover VK

更新日期：2009-05-01 00:00:00

abstract：:Not only is skin cancer by far the most common human cancer but also the incidence of skin cancer has been increasing at an alarming rate in recent decades. Fortunately, most people now realize that sun exposure causes unattractive photoaging and skin cancer, so they do apply sunscreens conscientiously. However, until...

journal_title：Toxicology and industrial health

authors： Burke KE,Wei H

更新日期：2009-05-01 00:00:00

abstract：:The objective of this study was to examine the potential of arsenate to induce cardiomyocyte cell death and to explore the cellular mechanisms of arsenate toxicity. Isolated cardiomyocytes in culture from embryonic chick hearts were treated with a pentavalent arsenic species (H3AsO4) or arsenate. Arsenate produced a s...

journal_title：Toxicology and industrial health

authors： Luong MW,Rabkin SW

更新日期：2009-04-01 00:00:00

abstract：:The Royal Australian Air Force (RAAF) has reported that personnel involved in F-111 fuel tank maintenance were concerned that exposure to a range of chemicals during the period 1977 to mid-1990s was the cause of health problems, including cancer. Particular concern was directed at SR-51, a desealant chemical mixture c...

journal_title：Toxicology and industrial health

authors： Oakes DJ,Ritchie HE,Woodman PD,Narup E,Moscova M,Picker K,Webster WS

更新日期：2009-02-01 00:00:00

abstract：:Chloroethane (CE) gas carcinogenicity is analyzed and determined from a National Toxicology Program (NTP) bioassay where an inhalation concentration of 15,000 ppm CE gas in air produced the highest incidence of an uncommon-to-rare tumor ever observed by the NTP. Persistently inhaled CE produces endometrial cancers in ...

journal_title：Toxicology and industrial health

authors： Holder JW

更新日期：2008-11-01 00:00:00

abstract：:The main objective of this study is to calculate the hours of diving in benzene-polluted waters acceptable for professional divers. We considered recommended absorption limit as that from pulmonary workplace absorption during an 8-h workday at recommended exposure limits set by the National Institute of Occupational S...

journal_title：Toxicology and industrial health

authors： Froom P

更新日期：2008-09-01 00:00:00

abstract：:As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These pro...

journal_title：Toxicology and industrial health

authors： Wilbur S,Wohlers D,Paikoff S,Keith LS,Faroon O

更新日期：2008-06-01 00:00:00

abstract：:The human teratogenic potential of chlordiazepoxide is debated. To study the effects on the fetal development of very large doses of chlordiazepoxide that were used for a suicide attempt during pregnancy, self-poisoned pregnant women were identified from patients in a toxicological inpatient clinic in Budapest, Hungar...

journal_title：Toxicology and industrial health

authors： Gidai J,Acs N,Bánhidy F,Czeizel AE

更新日期：2008-02-01 00:00:00

abstract：:The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Previous work has reported that JP-8 exposure is immunosuppressive. Exposure of mice to JP-8 for 1 h/day resulted in immediate secretion ...

journal_title：Toxicology and industrial health

authors： Harris DT,Sakiestewa D,Titone D,He X,Hyde J,Witten M

更新日期：2007-11-01 00:00:00

abstract：:The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Previous work has reported that JP-8 exposure is immunosuppressive. In the present study, the effects of in-utero JP-8 jet fuel exposure ...

journal_title：Toxicology and industrial health

authors： Harris DT,Sakiestewa D,He X,Titone D,Witten M

更新日期：2007-10-01 00:00:00

abstract：:Medicinal plants are increasingly being projected as suitable alternative source for the treatment of various diseases. However, toxic effects resulting from therapeutic bismuth compounds are still documented in animals and humans. This study described the genetic effects of five common lichen species and compared the...

journal_title：Toxicology and industrial health

authors： Geyikoglu F,Turkez H,Aslan A

更新日期：2007-09-01 00:00:00

abstract：:The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...

journal_title：Toxicology and industrial health

authors： Chou S,Colman J,Tylenda C,De Rosa C

更新日期：2007-05-01 00:00:00

abstract：:The anti-genotoxic potential of hydrated sodium calcium aluminosilicate (HSCAS) was investigated using sister chromatid exchanges (SCEs) induced by aflatoxin B1 (AFB1) as genotoxic endpoint in human lymphocytes. Whole blood samples from two healthy male donors were used for this experiment and the effects of different...

journal_title：Toxicology and industrial health

authors： Türkez H,Sişman T

更新日期：2007-03-01 00:00:00

abstract：:Polycyclic aromatic hydrocarbons have mutagenic and carcinogenic properties and some of them are classified as probable or possible human carcinogens. Aim of this study was to evaluate the genotoxic risk in workers exposed to diesel exaust. Environmental and biological monitoring exposure to polycyclic aromatic hydroc...

journal_title：Toxicology and industrial health

authors： Maina G,Manzari M,Palmas A,Passini V,Filon FL

更新日期：2007-02-01 00:00:00

abstract：:Maneb is a dithiocarbamate fungicide that contains manganese. Dithiocarbamates are considered to be chemicals of low toxicity. An experimental group (n = 10) received maneb (obtained from Hoecht-Shering) at a concentration of 250 ppm in distilled water five days a week (treatment time is three weeks). It was orally ad...

journal_title：Toxicology and industrial health

authors： Deveci E

更新日期：2006-10-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:Retinyl esters are the storage form of vitamin A in skin, and retinyl palmitate (RP) accounts for the majority of the retinyl esters endogenously formed in skin. RP is also obtained exogenously through the topical application of cosmetic and skin care products that contain RP. There is limited information on the penet...

journal_title：Toxicology and industrial health

authors： Yan J,Wamer WG,Howard PC,Boudreau MD,Fu PP

更新日期：2006-05-01 00:00:00

abstract：:Reports about vanadium (V) inhalation toxicity on the hematopoietic system, specifically about coagulation are limited. Therefore, we decided to evaluate the effects of V with a complete blood count and morphologic analysis of platelets on blood smears. CD-1 male mice inhaled V2O5 0.02 M 1 h twice weekly over 12 weeks...

journal_title：Toxicology and industrial health

authors： González-Villalva A,Fortoul TI,Avila-Costa MR,Piñón-Zarate G,Rodriguez-Laraa V,Martínez-Levy G,Rojas-Lemus M,Bizarro-Nevarez P,Díaz-Bech P,Mussali-Galante P,Colin-Barenque L

更新日期：2006-04-01 00:00:00

abstract：:This investigation gives detailed analysis of peripheral marker enzymes as well as neurobehavioral tests following chronic aluminium (Al) exposure (10 mg/kg b.w. for 12 weeks intragastrically). We observed a significant decrease in the levels of serum cholinesterase after toxicity. The enzymatic activity of cytochrome...

journal_title：Toxicology and industrial health

authors： Kaur A,Gill KD

更新日期：2006-02-01 00:00:00

abstract：:Flight personnel are exposed to cosmic ionizing radiation, chemicals (fuel, jet engine exhausts, cabin air pollutants), electromagnetic fields from cockpit instruments, and disrupted sleep patterns. Only recently has cancer risk among these workers been investigated. With the aim of increasing the precision of risk es...

journal_title：Toxicology and industrial health

authors： Buja A,Lange JH,Perissinotto E,Rausa G,Grigoletto F,Canova C,Mastrangelo G

更新日期：2005-11-01 00:00:00

abstract：:Cutting fluids can become contaminated with metals (e.g., nickel, Ni) and nitrosamines (e.g., N-nitrosodiethanolamine, NDELA) and there is concern that these classes of contaminants can modulate dermal disposition and ultimately the toxicity of cutting fluid additives, such as irritant biocides (e.g., triazine). Bioci...

journal_title：Toxicology and industrial health

authors： Baynes RE,Brooks JD,Barlow BM,Riviere JE

更新日期：2005-10-01 00:00:00

abstract：:In the last few decades the need for new approaches to assess DNA damage has been increasing due to the implications that different insults on genetic material may have on human health. In this context, the identification of how chemical agents with different mechanisms of action (i.e., antineoplastic drugs) damage DN...

journal_title：Toxicology and industrial health

authors： Mussali-Galante P,Avila-Costa MR,Piñón-Zarate G,Martínez-Levy G,Rodríguez-Lara V,Rojas-Lemus M,Avila-Casado MC,Fortoul TI

更新日期：2005-09-01 00:00:00

abstract：:Most of the mobile phones in Turkey emit 900 MHz radiation which is mainly absorbed by the skin and, to a lesser extent, muscle. The aim of this study was to investigate the effects the 900 MHz electromagnetic irradiation emitted by these devices on the induction of histopathologic changes in skin and the effect of me...

journal_title：Toxicology and industrial health

authors： Ozguner F,Aydin G,Mollaoglu H,Gökalp O,Koyu A,Cesur G

更新日期：2004-09-01 00:00:00

abstract：:The current study explores the effects of the inhalation of lead (Pb), Cd and its mixture (Pb-Cd) in a mice model, analysing metal concentrations in the lung, and the morphological modifications in the bronchiolar epithelium identified by scanning electron microscopy after eight weeks of inhalation. Our results indica...

journal_title：Toxicology and industrial health

authors： Fortoul TI,Avila-Costa MR,Espejel-Maya G,Mussali-Galante P,Avila-Casado Mdel C,Hernández-Serrato MI,Saldivar-Osorio L

更新日期：2004-06-01 00:00:00

abstract：:This investigation used a two-source capture-recapture method (CRM) for determining ascertainment and undercounts of non-national priority listed hazardous waste sites in the states of Arizona, Maine and Pennsylvania. These findings suggest that ascertainment of hazardous waste sites vary greatly, with some more accur...

journal_title：Toxicology and industrial health

authors： Lange JH,Chang YF,LaPorte RE,Mastrangelo G

更新日期：2003-07-01 00:00:00